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Among humans, opioids stimulate diminish both ACTH and corticosterone .

Naloxone, an opiate antagonist, stimulates the release of ACTH.

Some believe that a combination of the wrong foods and too many antibiotics and environmental toxins can damage the colon and lead to physical and behavioral problems, including autism.

The behavioral syndrome of autism includes abnormalities of language and thinking skills; repetitive behavior such as rocking; abnormal responses to sensations, people, events and objects; and self-injurious behavior.

Both types of action are probably mediated within the hypothalamus.

Lutenizing Hormone (LH), important in reproduction, is decreased by opioids, while opiate antagonists stimulate LH, both apparently by modulating LHRH release.

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Lewis Mehl-Madrona, "Effective Therapies for Autism and Other Developmental Disorders", recently published in Autism/Asperger's Digest Magazine.

Data regarding Thyroid Stimulating Hormone (TSH) are quite contradictory.

Both inhibitory and stimulatory effects have been described.

The opioid excess theory of autism says that autistic children are symptomatic due to excess opioid-like substances, whose effects on the brain produce the symptoms of autism.

Opioids and opioid-like substances, especially when in excess, have many effects upon hormones and hormonal regulation.

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